Department of Cell and Developmental Biology

Pediatric health conditions, their treatments and the related stress hinder the prefrontal cortex, which is the region of the brain associated with learning, memory and behavior. (istock)

Goal of new tissue-chip research is to assess efficacy of novel epilepsy drugs

An interdisciplinary team of Vanderbilt University researchers has received a two-year, $2-million federal grant to develop an “organ-on-chip” model for two genetic forms of epilepsy.

Epigenetics expert Allis set for Sept. 7 Discovery Lecture

Internationally known epigeneticist C. David Allis, Ph.D., will deliver the first Flexner Discovery Lecture of the academic year at 4 p.m. Thursday, Sept. 7, in room 208 Light Hall.

colored representation of cells and glia

Discovery sheds light on protein key to nerve cells’ myelin sheath

Genetic mutations in PMP22 (peripheral myelin protein 22) cause a variety of peripheral neuropathies, underscoring the importance of the protein to a healthy peripheral nervous system. But the precise function of PMP22, a major component of the myelin sheath that surrounds and insulates peripheral nerve cell axons, has been unclear.

NOTCH1 role in heart development

The identification of a genetic culprit for hypoplastic left heart syndrome could lead to new treatments for the condition.

Polarity protein role in cell survival

Vanderbilt investigators have identified an unexpected link between cell survival and the polarized delivery of proteins to the surface of mammary epithelial cells.

A molecular clue to longevity

In budding yeast, accumulation of a certain type of RNA in the nucleus increased life span, offering a new clue to longevity.

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