A trans-institutional team of researchers at Vanderbilt University Medical Center and Vanderbilt University has received an $11 million Cancer Moonshot grant to build a single-cell resolution atlas to map out the routes that benign colonic polyps take to progress to colorectal cancer, the third most common cancer among both men and women in the United States.

A protein called IRTKS helps build the microvilli that form the border of cells in the intestines, explaining why the protein is a frequent target of gut pathogens.

New findings demonstrate a previously unappreciated role of Shh signaling activity in the proliferation of CGNPs — the presumed cell-of-origin for a subset of the malignant pediatric brain tumor medulloblastoma.

Vanderbilt University’s most prestigious faculty honor for accomplishments in research, scholarship or creative expression was awarded to Kathleen Gould, PhD, during the Fall Faculty Assembly Aug. 23.

Studies in fruit flies have shed light on how the basement membrane — a sheet-like scaffold that wraps around most animal tissues — is repaired after being damaged.

New findings shed light on the formation of microtubule structures that support cellular processes ranging from cell division to intracellular transport.

New findings open opportunities to understand mechanisms of DNA repair for a toxic form of DNA damage.