Department of Medicine

photo of William Dupont
June 5, 2023

Study discovers that tumor mutation burden predicts survival outcome

The expected course of a patient’s cancer prognosis has traditionally been judged by its type, stage and microscopic aggressiveness, but patients with the same presentation can still have widely divergent outcomes. Researchers from Vanderbilt-Ingram Cancer Center have discovered that differences in tumor mutation burden are a major reason for this divergence.

By Tom Wilemon
June 5, 2023

Vanderbilt mourns loss of renowned clinical pharmacologist Jackson Roberts II, MD

Jackson Roberts II, MD, an internationally known clinical pharmacologist in the Vanderbilt University School of Medicine who helped define the role of lipid peroxidation and oxidative stress in human disease, died May 31 in Nashville. He was 79.

By Bill Snyder
May 31, 2023

Liquid biopsy test may detect early-stage and low DNA-shedding cancers

Vanderbilt research shows that a liquid biopsy-based multicancer early detection (MCED) test could detect 12 types of cancers, including low DNA-shedding cancers and early-stage cancers.

By Tom Wilemon
May 24, 2023

VUMC app used by research participants around the world

MyCap is a secure, customizable mobile computing application (for smartphone or tablet) used to collect data from research participants on a remote basis.

At Vanderbilt University Medical Center, where MyCap was created and launched in 2018, some 107 projects have used the app, and by 2021, research participants in 135 countries had installed the free app.

By Paul Govern
May 24, 2023

American Association of Critical-Care Nurses (AACN) recognizes Ely and Pun research team

The American Association of Critical-Care Nurses (AACN) is presenting the research team of Brenda Pun, DNP, RN, FCCM and E. Wesley Ely, MD, MPH, with its AACN Pioneering Spirit Award.

By Matt Batcheldor
May 24, 2023

Researchers probe the impact of sex and gender on human health

Vanderbilt University Medical Center’s Lea Davis, PhD, and longtime colleagues Ekaterina (Katya) Khramtsova, PhD, and Barbara Stranger, PhD, are among seven authors of a paper published May 11 in the journal Cell that outlines “best practices” for evaluating the impact of both sex and gender on human health.

By Bill Snyder
May 23, 2023

Diabetes Day celebrates 50 years of achievement, spotlights current investigations

Vanderbilt Diabetes Day, an annual event hosted by the now-named Vanderbilt Diabetes Research and Training Center (DRTC). The event spotlights the work of researchers, and this year also celebrated the 50-year anniversary of the DRTC.
By Jill Clendening
May 23, 2023

Treating kidney injury before it happens

Pretreatment of an animal model with a novel compound called PHAD reduced kidney injury, suggesting it may be a good candidate for preventing kidney injury in surgical patients.
By Sarah E. Glass
May 18, 2023

New view of mutations informs disease risk, treatment response

A transcontinental research effort led by scientists from Vanderbilt University Medical Center and the University of Michigan has upended some long-standing assumptions about mutations — how often they occur, what causes them and what they do.
By Bill Snyder
May 11, 2023

Bauml, Wright land eStar Physician Builder Awards

Vanderbilt radiologist and clinical informatics fellow Julie Bauml, MD, and internal medicine specialist Aileen Wright, MD, have received 2023 Physician Builder Awards.  
By Paul Govern
May 11, 2023

Lovly elected to American Association for Cancer Research board

Christine Lovly, MD, PhD, has been elected to the American Association for Cancer Research board of directors.
By Tom Wilemon
May 11, 2023

Genomic analysis of SCLC tumors reveals subtypes, offers cues toward personalized treatments

The largest genomic analysis ever conducted of small cell lung cancer tumors (SCLC) has identified genetic subtypes and provided insights into the mechanisms of this aggressive and deadly cancer.
By Tom Wilemon
May 9, 2023

Neural networks probe proteins

A machine learning method based on neural networks outperformed a mutational scanning model at identifying disease-causing mutations in an Alzheimer’s disease protein, suggesting the method could be useful for facilitating therapeutic design.
By Leigh MacMillan
1 … 30 31 32 33 34 … 125