Department of Medicine

Study finds similar success rates with two devices for breathing tube placement

Two devices for placing a breathing tube during critical illness had similar success rates for intubation on the first attempt, according to a study published Dec. 8 in JAMA.

From left, Ken Lau, PhD, Bob Chen, Qi Liu, PhD, Joseph Rolland, PhD, Martha Shrubsole, PhD, Robert Coffey, MD, and colleagues are studying how polyps develop into colorectal cancer, setting the framework for improved surveillance for the cancer utilizing precision medicine. (photo by Erin O. Smith)

Study sets framework for precision surveillance of colorectal cancer

Vanderbilt research has revealed some of the mechanisms by which polyps develop into colorectal cancer, setting the framework for improved surveillance for the cancer utilizing precision medicine.

Oral microbes and gastric cancer

Studies in three large population cohorts that include Asian, African American and European American people support a role for the oral microbiota — the collection of microbial species in the mouth — in gastric cancer development.

PHOTO: Members of the supermere discovery team include (front row from left) Qi Liu, PhD, Robert Coffey, MD, Qin Zhang, PhD, and (back row from left) James Higginbotham, PhD; Dennis Jeppesen, PhD; and Jeffrey Franklin, PhD. (hoto by Erin O. Smith)

“Supermeres” may carry clues to cancer, Alzheimer’s disease and COVID-19

Vanderbilt researchers have discovered a nanoparticle released from cells, called a “supermere,” which contains enzymes, proteins and RNA associated with multiple cancers, cardiovascular disease, Alzheimer’s disease and even COVID-19.

Cell signaling targets in leukemia

Vanderbilt researchers identified a critical role for IL-1beta signaling in leukemia cells with a certain mutation, suggesting this pathway may be a good target for novel treatments.

Gene discoveries give new hope to people who stutter

New research shows the potential to identify therapeutic directions that could improve outcomes for people who stutter.

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