diabetes

Study links gene network and pancreatic beta cell defects to Type 2 diabetes

A comprehensive study that integrates multiple analytic approaches has linked a regulatory gene network and functional defects in insulin-producing pancreatic beta cells to Type 2 diabetes.

Powers receives prestigious Veterans Affairs Middleton Award

Alvin C. Powers, MD, Joe C. Davis Professor of Biologic Science and professor of Medicine, Molecular Physiology and Biophysics, has received the 2023 William S. Middleton Award, the highest honor awarded by the Department of Veterans Affairs (VA) Biomedical Laboratory Research and Development Service.

Jordan Wright, MD, PhD, left, and Adel Eskaros, MBBS, PhD, are lead authors of the report on pancreatic exocrine-endocrine “crosstalk.” (photo by Susan Urmy)

Pancreas “crosstalk” may influence course of Type 1 and Type 2 diabetes

In the largest study of its kind, researchers at Vanderbilt have identified unexpected alterations in the exocrine tissues of the pancreas that occur in the two major forms of diabetes, and with aging and obesity.

Tirzepatide trial shows additional 21.1% weight loss following intensive lifestyle intervention

A Vanderbilt clinical trial evaluating the injectable prescription medication tirzepatide, showed an additional 21.1% weight loss after intensive lifestyle intervention in adults with obesity or who were overweight with weight-related comorbidities, excluding Type 2 diabetes.

Dame Frances Ashcroft Discovery Lecture postponed

From left, Sheila Collins, PhD, Ryan Ceddia, PhD, and Heidi Hamm, PhD, and their colleagues have identified a potential new approach to reducing the global impact of obesity and diabetes. (photo by Erin O. Smith)

Releasing a brake that drives obesity and diabetes

Vanderbilt researchers have uncovered a potential new way to help curb the rapidly rising worldwide prevalence of metabolic disorders, including obesity and diabetes.

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