Division of Clinical Pharmacology Archive — Page 1 of 10

Conceptual digital illustration of a polygonal human profile connected to a network of medical hexagons containing icons for healthcare, artificial intelligence, diagnostics, medicine, laboratory science, and body organs.
March 17, 2025

Where are all the Alzheimer’s drugs?

A new study will use innovative methods developed at VUMC to look for drugs already approved for other uses that could potentially be repurposed to treat Alzheimer’s.

Conceptual biotechnology scene showing gloved laboratory workers, test tubes, a pipette, and overlaid medical graphics including DNA-like molecular structures, human anatomy icons, a heartbeat waveform, charts, and a digital human figure.
January 23, 2025

Elite society honors two VUMC physician-scientists

The Young Physician-Scientist Award recognizes “notable achievements” by researchers who are within five years of their first faculty appointment.

Spilled salt shaker beside a stethoscope, with salt arranged in an ECG-like waveform on a dark surface.
October 21, 2024

Clue to salt-sensitive blood pressure found

Despite the well-established link between high salt intake and cardiovascular disease and stroke, the mechanism of SSBP is poorly understood, and it remains an untreatable cardiovascular risk with no widely available diagnostic tool.

Conceptual illustration of a leafy tree formed by winding groups of diverse people, representing human connections and shared ancestry.
September 27, 2024

Distant relatedness in biobanks harnessed to identify undiagnosed genetic disease

VUMC researchers have developed a genetic method that clusters distantly related people to find rare variants that were present in a common ancestor.

Abstract side-profile silhouette outlined in glowing white and blue light against a dark background, surrounded by colorful blurred circles.
September 9, 2024

Peptide discovery could advance treatment of high blood pressure

VUMC researchers found that peptides modified by highly reactive compounds called isolevuglandins activated T cells and promoted hypertension in mice. Their first-ever isolation of such peptides is a step toward potentially intervening in this pathologic process.

Illustration of a blood vessel cut open to reveal yellow fatty plaque narrowing the channel, with red blood cells flowing around the obstruction.
August 13, 2024

$3.4 million research grant targets risk of heart attack, stroke

Making innovative use of observational data, researchers hope to gain new understanding of patient risk and identify existing drugs to lower risk.