Division of Clinical Pharmacology

People whose white blood cell levels are near the edge of the “healthy” reference range will hit a clinical decision point that has consequences such as diagnostic procedures and altered treatments.

TPC’s help hotline —1-800-222-1222 — is staffed by nurses, pharmacists, physicians and board-certified medical toxicologists who are specially trained to assist callers.

Factors other than oxidative stress can modify the levels of biomarkers called isoprostanes that are commonly used in both experimental and clinical research, suggesting that additional standards need to be developed.

An analysis of genomic data from nearly 250,000 participants in the National Institutes of Health’s All of Us Research Program has identified more than 275 million previously unreported genetic variations, nearly 4 million of which have potential health consequences.

Genetic analyses suggest that branched chain amino acids may be a sensitive biomarker of early or subclinical Type 2 diabetes and could be used to identify risk and implement preventive measures.

Accounting for genetic variability in biomarkers not associated with cancer risk could avoid unnecessary diagnostic procedures, Vanderbilt researchers found.

A new study will explore the link between salt taste sensitivity and salt intake, blood pressure, hypertension, and genetic variations in individuals of African descent.