Variation in the gene for the beta-1 adrenergic receptor increases the risk that a patient will have an abnormal heart rhythm after cardiac surgery.

Removal of the neurotransmitter norepinephrine from the space outside cells plays an important role in the regulation of bone remodeling.

Tacrolimus is essential for patients receiving new hearts, kidneys and other organ transplants. The drug suppresses the body’s immune system, helping to prevent rejection.

Reducing heart muscle response to calcium could decrease the risk of fatal arrhythmias after heart attacks.

Since it was founded in 1963, the Vanderbilt Division of Clinical Pharmacology has pioneered “translational science” and continues to transform medical practice worldwide, speakers at the division’s 50th anniversary scientific symposium said last week.

The 50th anniversary of the Division of Clinical Pharmacology will be celebrated Thursday, June 6, with a daylong scientific symposium and luncheon in the Student Life Center.

Dan Roden, M.D., assistant vice chancellor for Personalized Medicine and William Stokes Professor of Experimental Therapeutics, received a 2012 Distinguished Scientist Award at the annual Scientific Sessions of the American Heart Association (AHA) last week in Los Angeles.