Division of Epidemiology

New gene discoveries target uterine fibroids

The research is another step toward development of targeted therapies aimed at reducing the incidence and medical burden of this common condition.

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Study in multiancestry populations uncovers new insights into breast cancer genetics 

The study identified 332 independent association signals for breast cancer risk, including 131 signals not previously reported.

Novel genetics approach enhances discovery of disease risk genes

VUMC researchers applied the new approach to large GWAS datasets for breast, prostate and lung cancers, and three brain disorders.

Southern Environmental Health Study recruiting participants 

People who sign up can help researchers assess whether environmental factors may be the culprits behind the region’s higher cancer burden.

VUMC, Nigeria teaching hospital to study genetic risk of fibroids based on regional African ancestry

The research team will analyze existing genome-wide association study data and RNA sequencing to compare fibroid development patterns in Nigerian women and U.S. Black women, which could point to targeted therapies and management strategies for affected women.

Epigenetic change to DNA associated with cancer risk in ‘multiomics’ study

The new study identifies 4,248 CpG sites associated with the risk of seven different types of cancer: breast, colorectal, renal cell, lung, ovarian, prostate and testicular germ cell cancers.

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