immunology

A new study led by Vanderbilt University Medical Center researchers has identified key immune cell populations that predict how well pediatric hematopoietic stem cell transplant (HCT) recipients will respond to the influenza vaccine.

Glucose metabolism influences the qualities of activated, mature B cells — white blood cells that are required for antibody-mediated immune responses, Vanderbilt researchers discovered.

Researchers at Vanderbilt University Medical Center have published the largest known single-site adipose tissue atlas — a comprehensive, detailed map of the cells, structures and molecules within a specific tissue or organ, designed to support open-ended study.

Vanderbilt researchers found that T cells become “exhausted” within hours of encountering a tumor, challenging existing ideas about how T cells become dysfunctional.

A case study of a rare disorder uncovers roles for the protein dysbindin in the adaptive immune response and suggests that mutations may underlie some cases of very early onset inflammatory bowel disease.

A new technique will allow researchers to track subsets of immune cells that patrol and defend the lungs, to better understand the roles of these cells during lung inflammation, infection and injury.

Understanding how hellbenders — large, fully aquatic salamanders — fight fungal pathogens and disease is important for protecting these unique stream predators; Vanderbilt researchers add new insights.