Jacek Hawiger

The team studying how to control sepsis in the lungs and kidneys includes, from left, Huan Qiao, MD, PhD Jacek Hawiger, MD, PhD, Jozef Zienkiewicz, PhD, and Yan Liu, MD, MS. (photo by Erin O. Smith)
August 21, 2023

Study reveals genomic code for sepsis in the lungs and kidneys

Researchers at Vanderbilt University Medical Center and the Nashville Veterans Affairs Medical Center have “cracked” the genomic code for sepsis in the lungs and kidneys.

By Bill Snyder
Jacek Hawiger, MD, PhD, third from right, with study team members, from left, Katherine Gibson-Corley, DVM, PhD, Yan Liu, MD, Jozef Zienkiewicz, PhD, Huan Qiao, MD, PhD, and Ruth Ann Veach.
November 10, 2022

Hawiger still blazing a trail in inflammation research

Vanderbilt research describes a new investigational peptide drug that can penetrate immune and nonimmune cells, and block inflammatory signaling in a preclinical model of atopic dermatitis — eczema.

By Bill Snyder
June 8, 2021

VUMC team develops potential treatment for life-threatening microbial inflammation

A cell-penetrating peptide developed by researchers at Vanderbilt University Medical Center can prevent, in an animal model, the often-fatal septic shock that can result from bacterial and viral infections.

By Bill Snyder
November 5, 2019

Endotoxin shock protector

A novel tool developed by Vanderbilt scientists protects animals from endotoxin shock and can be used for mechanistic analyses of inflammation due to microbial and other insults.

By Bill Snyder
storming night with many bolts of lightning
June 22, 2017

VU scientists report a way to calm the sepsis “storm”

Researchers at Vanderbilt University Medical Center (VUMC) have found a way to calm the “genomic storm” that triggers the often-lethal consequences of sepsis.

By Bill Snyder
December 9, 2016

Protecting the blood-brain barrier

Vanderbilt investigators have discovered how a promising cancer immunotherapy causes brain swelling, findings that could lead to ways to protect brain function while fighting cancers.

By Sanjay Mishra
November 25, 2016

Nine Vanderbilt faculty members elected AAAS fellows

Nine Vanderbilt University faculty members have been elected fellows of the American Association for the Advancement of Science this year.
By Bill Snyder
October 28, 2014

Peptide quells “genomic storm”

A cell-penetrating peptide developed at Vanderbilt blocks the signaling pathways that lead to lethal shock caused by bacterial infection.
By T.J. Utset
August 1, 2014

Anti-inflammatory protein “rheostat” sheds light on leaky blood vessels

Vanderbilt researchers have discovered that the protein CRADD counteracts inflammatory injury to endothelial cells, which could assist the development of new therapies for inflammatory vascular disorders.
By Emily Poulin
October 11, 2013

New target for stopping inflammation

Importin alpha 5, a member of a family of proteins that “shuttle” other proteins into the nucleus, is a potential new target for drugs to treat inflammatory diseases.
By Bill Snyder
August 8, 2013

Nuclear shield against cell death

The protein SARM appears to protect cells from inflammation-driven death by stabilizing the nuclear laminin scaffold.
By Bill Snyder
April 18, 2013

Early study reveals ‘nuclear’ strategy for atherosclerosis

Vanderbilt University scientists have discovered a potential new strategy for lowering cholesterol and triglyceride levels and stopping atherosclerosis and fatty liver disease.
By Bill Snyder