SJS and TEN occur when a medication triggers the immune system to attack the body’s own skin and mucous membranes.
The discovery could improve safety of allopurinol for millions by expanding genetic screening.
Overall, there was a 14% reduction in skin cancer risk. When nicotinamide was taken after a first skin cancer, the risk reduction rose to 54%.
Researchers recommended long-term follow-up for patients by dermatologists familiar with cirAEs and consideration of corticosteroid-sparing treatment options.
Vanderbilt research shows that 10-second videos of white blood cell motion in the skin’s microvasculature greatly improved the prediction of which stem cell and bone marrow transplant patients would have a relapse of their blood cancer.
The billing codes in electronic health records are useful for counting skin cancers over time — an important metric for cancer risk assessment and prevention.