JAMA Network Open (journal) Archive — Page 2 of 5

Julia Sheffield, PhD, smiles while seated at a desk beside a computer monitor, telephone, coffee mug, houseplants, and a stained-glass lamp.
October 22, 2025

Behind the curtain: Secrets of the volatile, delusional brain 

The VUMC approach, based on the “Feeling Safe Program” developed by British psychologist Daniel Freeman, targets specific factors that contribute to persecutory delusions, including worry, safety behaviors, avoidance and hallucinations (such as hearing voices).

Healthcare professional in blue scrubs holding a tablet, overlaid with glowing digital medical interface graphics including a heart-monitor waveform, hearts, lungs, and connected data points.
September 5, 2025

AI tools could shorten ‘diagnostic odyssey’ for patients with rare diseases

Large language models achieved diagnostic rates of 13.3% and 10.0%, compared to the historical clinical review rate of 5.6%, and they suggested next steps to evaluate the suggested diagnoses.

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August 6, 2025

Study demonstrates burden of potentially preventable hospitalizations for pneumococcal pneumonias among adults in Tennessee and Georgia 

Community-acquired pneumonia refers to a case of the disease contracted without prior exposure to a health care setting.

Aimal Khan, MD, with one of the 3D models he created to use during preoperative consultations. (photo by Donn Jones)
June 9, 2025

Presurgery consults with patients using 3D models improve shared decision-making and reduce anxiety 

The models allowed patients to easily distinguish the ascending colon from the sigmoid colon, along with other parts of the digestive system.

Black silhouette of a person standing against a textured grayscale watercolor background.
May 8, 2025

Veterans with depression have increased risk of heart failure: study

The findings give patients and clinicians have another reason to screen for and treat depression in order to prevent potential future heart failure.

(Adobe Stock)
March 12, 2025

‘Trajectories’ of poor sleep over time may shorten your life: study

Long-term trajectories of irregular sleep durations outside the optimal range (more or less than the healthy duration of seven to nine hours of sleep per night) increased the risk of death from all causes by as much as 29%.