JAMA Network Open (journal) Archive — Page 1 of 5

Unidentified pregnant person in a black top holds a handful of assorted pills while resting the other hand on their abdomen.
October 19, 2026

Study advances understanding of SSRI use during pregnancy

“One of the takeaways (of this study) was that if you need to be on an SSRI, stay on it, but make sure to deliver in a place that can take care of the baby,” said Jennifer Sucre, MD, co-corresponding author of the study.

(iStock)
September 14, 2026

How ‘mismatched donors’ are opening new doors for blood cancer patients

The ACCESS trial allowed mismatched, unrelated donors for blood cancer patients who didn’t have a perfect match for a stem cell transplant; the trial enrolled a more varied population of patients.

Conceptual biotechnology scene showing gloved laboratory workers, test tubes, a pipette, and overlaid medical graphics including DNA-like molecular structures, human anatomy icons, a heartbeat waveform, charts, and a digital human figure.
September 2, 2026

Millions get wrong genetic test, study finds

A study shows current testing is providing false reassurance about genetic disposition for a rare life-threatening drug reaction.

Scored round pale pink tablet standing upright on a surface, with blurred colorful pills in the background.
July 24, 2026

Study shows one-fifth of prescribed cancer drugs initially denied coverage in Medicare were overturned when reviewed

The most common reason for initial denials was “non-medically acceptable” indications, or drugs prescribed “off-label,” which means using a drug outside its formally approved indication.

(iStock)
May 18, 2026

Study finds benefit in genotype-guided care for depression

Genetic variants known to slow or speed metabolism of drugs for depression and anxiety disorders are very common.

Silhouette of a solitary person standing in a white beam of light beneath a black spotlight against a yellow background.
March 10, 2026

Loneliness is a critical step on the road to suicide: Study

Mental health treatment is often out of reach. A person-centered approach to reducing loneliness that helps people engage with others might be more feasible.