James Goldenring Archives
New marker for metaplasia
Oct. 14, 2021—A protein that transports water, called aquaporin 5, is expressed by cells undergoing changes that may increase risk for gastric cancer development, Vanderbilt researchers discovered.
Motor protein linked to intestinal cell differentiation
Aug. 5, 2021—The motor protein MYO5B, a cause of the congenital intestinal disorder microvillus inclusion disease, does more than move cellular cargo, Vanderbilt researchers have discovered.
Factor involved in stomach injury response identified
Oct. 15, 2020—Researchers at Vanderbilt University Medical Center have identified a key factor that coordinates the body’s repair response to severe injury in the stomach caused, most commonly, by infection by the bacterium Helicobacter pylori.
VUMC study sheds light on gastric cancer development
Jan. 16, 2020—VUMC researchers have created the world’s first laboratory model of precancerous changes in the lining of the stomach, a scientific tour de force that is helping to unlock the mysteries of gastric cancer development.
Team set to study undiagnosed congenital diarrhea in infants
Oct. 24, 2019—Researchers at four institutions, including Vanderbilt, have been awarded a five-year, $9.4 million federal grant to tackle undiagnosed congenital diarrheas caused by a single gene mutation.
Major grant to bolster research on inflammation-related cancers
Jan. 23, 2019—Cancer Research UK has awarded a 20-million-pound grant (about $25 million U.S.) to a team of international investigators, including Vanderbilt’s James Goldenring, MD, PhD, to study inflammation-related cancers.
Burroughs Wellcome Fund award expands opportunities for physician-scientists
Jun. 21, 2018—Vanderbilt University has received a five-year, $2.5-million Physician Scientist Institutional Award from the Burroughs Wellcome Fund to help bolster the dwindling number of active physician-scientists in the United States.
Research sheds light on how microtubules are assembled
Jan. 4, 2018—Microtubules are the “railroad tracks” essential for moving intracellular “freight” around in the cell. They’re also part of the spindle that pulls the two centrosomes apart during cell division.
Study seeks to reverse precancerous stomach lesions
May. 4, 2017—Vanderbilt University Medical Center cancer researcher James Goldenring, M.D., Ph.D., has received a two-year, $200,000 grant from the DeGregorio Family Foundation in Pleasantville, New York, to begin clinical trials of a potential approach for reversing precancerous stomach lesions.
Goldenring recognized for research mentorship efforts
Jun. 23, 2016—James Goldenring, M.D., Ph.D., co-director of the Epithelial Biology Center at Vanderbilt University Medical Center (VUMC), has received a Research Mentor Award from the American Gastroenterology Association Institute Council for “outstanding research mentorship.”
Study suggests cancer’s ‘clock’ can be rewound
Mar. 17, 2016—Researchers at Vanderbilt University Medical Center have “turned back the clock” in a mouse model of metaplasia — precancerous stomach lesions — raising hopes that gastric cancer, a worldwide scourge that’s rising in the United States, can be prevented.
Clinicians, researchers team to treat boy’s rare disorder
Mar. 3, 2016—Test after test failed to reveal why Denny Majano wasn’t gaining weight or why he suffered from severe, chronic diarrhea. At 5 weeks old, instead of gaining weight as newborns should, Denny had lost a pound since birth.
