JCI Insight (journal) Archive — Page 1 of 2
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April 21, 2022
VUMC a national leader in physician-scientist training
Physician-scientists from Vanderbilt University Medical Center were well represented at the recent annual meeting of the American Society for Clinical Investigation (ASCI), Association of American Physicians (AAP) and the American Physician-Scientist Association. -
February 2, 2022
VUMC study raises hope for improving treatment of kidney disease
Vanderbilt research has revealed an important mechanism in the kidney by which a cell surface receptor known as DDR1 fans the flames of inflammation and fibrosis that ultimately lead to kidney failure. -
January 19, 2022
Study identifies molecular trigger of severe injury-induced inflammatory response
Vanderbilt researchers have discovered that early inappropriate activation of the enzyme plasmin caused by severe injury is a trigger of systemic inflammatory response syndrome and resulting organ failure. -
September 16, 2021
‘Pre-conditioning’ restores immune tolerance
A treatment targeting T-cell metabolism could reinvigorate immune tolerance mechanisms to combat autoimmune disease and transplant rejection, Vanderbilt researchers discovered. -
August 5, 2021
Motor protein linked to intestinal cell differentiation
The motor protein MYO5B, a cause of the congenital intestinal disorder microvillus inclusion disease, does more than move cellular cargo, Vanderbilt researchers have discovered. -
August 20, 2020
A “torque” for tumor blood vessels
Vanderbilt scientists have discovered a new target for normalizing tumor blood vessels to improve cancer immunotherapies. -
June 4, 2020
Protecting the injured kidney
Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it.