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Jonathan Schoenecker Archives

Study identifies molecular trigger of severe injury-induced inflammatory response

Jan. 19, 2022—Vanderbilt researchers have discovered that early inappropriate activation of the enzyme plasmin caused by severe injury is a trigger of systemic inflammatory response syndrome and resulting organ failure.

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Calcification after severe injury

Feb. 23, 2021—Vanderbilt researchers have linked bone-related complications of severely injured patients — findings that could help minimize these complications.

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Keeping bone in its place

Apr. 11, 2019—Jonathan Schoenecker and colleagues have discovered a new mechanism for the formation of bone in soft tissues — a complication of severe injuries that causes pain and limits mobility.

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Pediatric and adult orthopaedic surgeons bridge age gap on hip preservation

May. 31, 2018—Tristan Miranda spent the waning days of summer last year on a California beach doing hip pivots on a surfboard — an extraordinary feat for someone who underwent hip surgery just three months earlier.

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My Southern Health: We’ve been thinking about bone health backward

Feb. 2, 2018—We often think about bone health from a nutritional standpoint. We analyze what we can put into our bodies to feed our bones—through diet or supplements—to make them stronger. That’s the wrong way to think about it, says Assistant Professor of Orthopaedic Surgery and Rehabilitation Jonathan Schoenecker.

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Celebration honors 11 university endowed chair holders

Oct. 25, 2017—Eleven Vanderbilt University faculty members named to endowed chairs were honored Oct. 23 during a festive celebration at the Student Life Center.

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Plasmin prevents muscle ‘hardening’ after injury: study

Dec. 8, 2016—Vanderbilt researchers have made the surprising discovery that the protease plasmin, known for its clot-busting role in the blood, protects soft tissue from turning to bone after severe injuries and certain orthopaedic surgeries.

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The most popular research stories of 2015

Dec. 28, 2015—With discoveries ranging from the origins of consciousness to the end of the universe, 2015 was a year of incredibly diverse research at Vanderbilt University.

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VUMC study shifts thinking on how bone fractures heal

Aug. 13, 2015—New findings show that fibrin, a protein that was thought to play a key role in fracture healing, is not required, shifting understanding of how fractures heal.

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Stuffed animals bring bacteria to OR

Apr. 17, 2015—Stuffed animals that pediatric patients bring to the operating room are a reservoir of bacteria that can be effectively sterilized in a household washer/dryer the day before surgery.

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Aggressive bone cancers build more blood vessels

Sep. 3, 2014—A subpopulation of bone cancer cells may be responsible for driving clinically aggressive behavior, suggesting new treatment options.

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