Chloride plays a key role in the formation of the basement membrane, a suprastructure on the outside of cells that undergirds and guides the function of most of the tissues of the body.

The proteins that control entry and exit from the cell nucleus influence aging, Vanderbilt researchers have discovered.

The potential for long-range signaling factors – such as those identified in the current study – to regulate stem cell behaviors has implications in tumor progression and metastasis.