Journal of Lipid Research

skin cross section
May 18, 2023

A critical skin enzyme

Detailed studies of the enzymatic properties of PNPLA1 support the requirement for this protein in skin barrier formation.

By Leigh MacMillan
February 7, 2023

A new view of a cholesterol carrier

Vanderbilt researchers developed a novel method to measure small RNAs carried by HDL and demonstrated that these molecules circulate in greater concentrations than previously believed and are likely to contribute to communication between immune cells.

By Kelsey Pinckard 
February 14, 2019

The yin and yang of cell signaling

Larry Marnett and colleagues have explored the role of two enzymes in metabolizing molecules associated with cell proliferation, inflammatory processes and neurological diseases.

By Sanjay Mishra
April 19, 2018

How the skin protects

Treatments for common skin conditions such as atopic dermatitis may be improved by understanding the enzymes responsible for forming the skin’s water-tight barrier.

By Sanjay Mishra
obesity or overweight belly
September 15, 2017

Inhibiting obesity

An enzyme in the gut – NAPE-PLD – is required for the action of signaling molecules that reduce food intake and weight gain.

By Leigh MacMillan
January 13, 2016

Platelet protein modification

Vanderbilt investigators have identified a new biomarker to assess platelet function.

By Leigh MacMillan
November 25, 2014

Protein implicated in atherosclerosis

Vanderbilt researchers have discovered a new target for the prevention of atherosclerotic plaque development and cardiovascular disease.
By VUMC News and Communications
October 4, 2012

An orphan enzyme’s purpose

“Orphan” enzyme may play role in cancer growth, new research suggests.
By VUMC News and Communications
March 21, 2012

Obesity turns “good” cholesterol bad

Studies offer new insights into how obesity impairs the function of HDL, the “good” cholesterol.
By Leigh MacMillan
March 3, 2012

Reversing lipid woes in cystic fibrosis

Abnormal levels of fatty acids in the blood and tissues of patients with cystic fibrosis may be reversed by supplementation with the fatty acids DHA and EPA.
By Leigh MacMillan