kidney disease

Three-dimensional imaging of kidney tubules (yellow and green noodle-like structures) under low potassium conditions, which puts the kidney into a state of metabolic overdrive and causes cardiovascular problems.
August 5, 2024

Low potassium ‘turns on’ kidney proximal tubule: study

A kidney protein that responds to low levels of blood potassium — which can cause high blood pressure and cardiovascular problems — may be a target for new therapeutics.

By Leigh MacMillan
February 7, 2024

VUMC study finds molecular switch key to repair of kidney damage

Researchers at Vanderbilt University Medical Center have identified Rac1, a molecular switch that regulates the actin cytoskeleton of epithelial cells in the collecting ducts, as a driver of post-obstructive kidney repair.

By Bill Snyder
November 21, 2023

VUMC scientists discover key step to kidney fibrosis

Researchers at Vanderbilt University Medical Center for the first time have shown that activation of the epidermal growth factor receptor (EGFR) is essential for the development of kidney fibrosis, tissue scarring following injury that can lead to kidney failure.

By Bill Snyder
October 5, 2023

Kidney disease gene also has a protective mutation

African Americans have long been known to be at increased risk of kidney disease due to a dangerous genetic mutation that creates a hole in the kidney cells, but Vanderbilt researchers have now discovered a protective genetic mutation that covers the hole to eliminate the risk.

By Craig Boerner
May 8, 2023

Improved imaging for kidney disease

Vanderbilt researchers identified optimal MRI parameters for estimating the severity of polycystic kidney disease, a common inherited disorder that can lead to end-stage renal failure.

By Leigh MacMillan
January 19, 2023

Low potassium injures kidney

Vanderbilt researchers have discovered that low dietary potassium causes direct kidney injury, suggesting potential new targets for treating chronic kidney disease.

By Leigh MacMillan
January 5, 2023

VUMC researchers upend dogma about vasopressin production

Vanderbilt investigators have discovered that vasopressin, which has long been thought to be produced only in the brain, is also produced in the kidney.
By Leigh MacMillan
December 15, 2022

Novel therapeutic target identified for chronic kidney disease

Vanderbilt investigators have discovered a molecular mechanism that promotes chronic kidney disease following kidney injury.
By Leigh MacMillan
December 15, 2022

Reduced kidney function may cause cardiovascular disease: study

An international team of investigators has found that mild to moderate reduction in kidney function may cause cardiovascular disease, even in people without symptoms of heart disease or diabetes.
By Bill Snyder
December 15, 2022

Nephrology society lauds Bock’s research on kidney development

Vanderbilt's Fabian Bock, MD, PhD, won two awards at the Basic Research Forum for Emerging Kidney Scientists, presented virtually by the American Society of Nephrology and American Physiological Society.
By Bill Snyder
November 17, 2022

VUMC adopts updated kidney function equation to better guide patient care decisions

In December Vanderbilt University Medical Center will again update the equation used for estimating kidney function with the goals of improving health equity and better guiding patient care decisions.
By Jill Clendening
November 17, 2022

Study supports removing race from estimate of kidney function

An in-depth analysis by Vanderbilt investigators of published research studies supports removing race from the calculation of estimated glomerular filtration rate (eGFR) — an assessment of kidney function.
By Leigh MacMillan
October 27, 2022

Terker selected as VUMC Discovery Scholar in Health and Medicine

By Bill Snyder
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