Nature Communications (journal)

Adriana Hung, MD, MPH, talks with patient Sylvester Norman, who is participating in the VA Department’s Million Veteran Program.

Study shines light on architecture of kidney disease

A study of 280,000 U.S. veterans, including 56,000 African Americans, has identified in greater detail than ever before the genetic architecture of kidney function and chronic kidney disease (CKD), according to researchers at Vanderbilt University Medical Center and their colleagues.

Pampee Young, MD, PhD, left, Sarika Saraswati, PhD, and colleagues are studying the different ways fibroblasts function following tissue injury.

Cellular engines of wound repair have distinct roles

Vanderbilt investigators have discovered that, in contrast to prevailing dogma, fibroblasts are not all alike; instead, they have distinctive functions following tissue injury.

Rehab technique may boost supply of donor lungs

A new regeneration technique could potentionally add to a limited supply of donor organs for an increasing population with end-stage lung disease.

Researchers putting the brakes on lethal childhood cancer

Malignant rhabdoid tumor (MRT) is one of the most aggressive and lethal childhood cancers. Although rare — about 20 to 25 new cases are diagnosed annually in the United States — there is no standard effective treatment for the disease, which is driven by loss of an anti-cancer protein called SNF5. The chances are very small that a child will survive a year after MRT diagnosis.

Exploring the brain’s white matter

New comprehensive functional MRI measurements point to the need to update models for assessing brain white matter activity and physiology.

The exocyst dynamo

New methods have revealed details of vesicle trafficking in cells and are applicable to any protein complexes, potentially revolutionizing our understanding of cell dynamics.

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