obesity Archives
Immune cells drive beta cell loss in Type 2 diabetes
Sep. 8, 2022—Vanderbilt researchers have discovered details of pancreatic beta cell loss — and potential therapeutic targets — during conditions of overnutrition, as occurs in obesity.
Inflammatory driver of obesity
Aug. 25, 2022—Blocking the EGF receptor signaling pathway in immune system macrophages represents a new target for improving insulin resistance in people with obesity.
Study sheds light on the dark side of obesity
May. 12, 2022—Vanderbilt research that promotes the anti-inflammatory pathway in macrophages could also reduce some of the bad side effects of obesity.
Reducing obesity-related inflammation
Mar. 24, 2022—A treatment that increases levels of lipid signaling molecules reduced adipose tissue inflammation in obese adults, suggesting this pathway may be a valuable target for modulating fat and systemic inflammation.
New insights into hypothalamic obesity
Feb. 10, 2022—A common Type 2 diabetes treatment being tested for hypothalamic obesity had unexpected results on weight loss and total energy expenditure, Vanderbilt researchers report.
Regulators of fat cell metabolism
Sep. 7, 2021—Vanderbilt researchers have discovered new details of the regulation of fat cell metabolism, findings that are important for combating obesity.
Obese children, young adults at higher risk for thyroid cancer
Aug. 26, 2021—Children and young adults who are obese are at greater risk for malignant thyroid nodules, according to new study from Monroe Carell Jr. Children’s Hospital at Vanderbilt.
Study reveals missing link between high-fat diet, microbiota and heart disease
Aug. 12, 2021—A high-fat diet disrupts the biology of the gut’s inner lining and its microbial communities — and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science.
V Scholar Award to support Byndloss’ cancer research
Nov. 18, 2020—Mariana Byndloss, DVM, PhD, assistant professor of Pathology, Microbiology and Immunology, has received a V Scholar Award to support her studies of the links between obesity, the gut microbiome and colorectal cancer.
New treatment for a rare obesity
Nov. 3, 2020—Diabetes drugs known as GLP-1 receptor agonists, such as exenatide (Byetta), are a promising and safe treatment for a rare form of obesity.
New tools to study bioactive lipids
Jul. 14, 2020—Vanderbilt researchers have identified and characterized inhibitors of an enzyme that synthesizes lipid signaling molecules with roles in energy balance, inflammation and addiction.
Biomarker in saliva predicts childhood obesity risk: study
Mar. 5, 2020—A molecular marker in saliva is associated with the emergence of childhood obesity in a group of preschool-aged Hispanic children.
