Vanderbilt University Medical Center has received a $7 million, five-year funding award from the Patient-Centered Outcomes Research Institute to compare two sedatives used to place breathing tubes in the emergency department or intensive care unit.

Vanderbilt University Medical Center is part of a select group of health systems nationwide brought together to accelerate the implementation of medical research results that will improve patient outcomes.

Vanderbilt researchers suggest that to reduce treatment-related regret for men with localized prostate cancer, treatment preparation should focus on shared decision-making and aligning patient expectations with treatment toxicity.

Vanderbilt's STAR Clinical Research Network has been approved for an additional $8.9 million in funding from the Patient-Centered Outcomes Research Institute (PCORI) to support its efforts to improve health care throughout the Southeast and across the United States.

According to an innovative large-scale clinical trial reported last week in the New England Journal of Medicine, a single daily baby aspirin (81 mg) or a single daily adult aspirin (325 mg) are equally safe and effective for prevention of adverse cardiovascular events for patients with established atherosclerotic cardiovascular disease.

Up to 25% of patients with acute heart failure (AHF) face mortality or hospital readmission within one month after being treated in the emergency department (ED).

A study group of more than 600,000 patients with type 2 diabetes, identified from electronic medical records in the PCORnet national research network, could be valuable for assessing the safety of type 2 diabetes drugs.