Science Signaling (journal)

June 22, 2023

Pathways to a healthy liver

Hepatic stellate cells maintain liver mass and function; the signaling factors they use could be exploited therapeutically to promote liver regeneration and inhibit cancerous proliferation, Vanderbilt researchers suggest.

By Bill Snyder
March 7, 2019

Vanderbilt scientists report new modeling of brain signaling

The release of neurotransmitters and hormones in the body is tightly controlled by complex protein machinery embedded in cell membranes.

By Bill Snyder
3d rendering white blood cells with red blood cells
May 9, 2018

Putting the brakes on sepsis

An enzyme called PTEN reduces inflammatory signaling and mortality in sepsis, suggesting it may be a good therapeutic target for this life-threatening complication of infection.

By Leigh MacMillan
September 28, 2017

Cellular calcium handling in diabetes

Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health.

By Leigh MacMillan
bacteria microbiome
February 3, 2017

Bacterial signaling systems

Vanderbilt researchers have identified a unique example of communication between bacterial signaling systems, which may have relevance for antibiotic resistance.

By Leigh MacMillan
October 26, 2016

Single-cell study of tumor samples

A new method for analyzing cells in fixed biopsy tissues from patients by guide personalized treatment strategies for cancer.

By Leigh MacMillan
August 12, 2016

New culprit in nerve degeneration

Vanderbilt researchers have discovered that regulation of cell volume plays a role in nerve degeneration and peripheral neuropathies.
By Leigh MacMillan
October 4, 2012

Proteins help flip tumor’s invasive switch

Vanderbilt investigators have identified how two key components of cancer's invasive "switch" — the series of signaling events that turn on a tumor cell’s invasive behavior — work together.
By Leigh MacMillan