Research

Sweatt, Tansey discuss influence of epigenetics on research

Basic research underway at Vanderbilt University Medical Center is raising hopes that one day it will be possible to reverse memory loss in people with Alzheimer’s disease and stop a major driver of cancer in its tracks.

Researchers find novel mechanism of resistance to anti-cancer drugs

Vanderbilt investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings, reported this week in Nature Medicine, suggest a strategy for overcoming this resistance.

Cellular calcium handling in diabetes

Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health.

Excess dietary manganese increases risk of staph infection in heart

Too much dietary manganese — an essential trace mineral found in leafy green vegetables, fruits and nuts — promotes infection of the heart by the bacterium Staphylococcus aureus (“staph”).

New lab formulary improves quality, cuts cost

An effort at Vanderbilt University Medical Center (VUMC) to enhance clinical decision making through cross-departmental collaboration and effective use of diagnostics has improved patient care and saved the institution more than $1 million in 2016, VUMC officials reported this week.

Pregnant woman holding pill pack

NSAIDs, genetics and miscarriage

A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage.

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