Research

From left, Jennifer Pietenpol, PhD, Eric Farber-Eger, Lauren LeStourgeon, MPH, Luisella Spiga, PhD, and John Kuriyan, PhD.

VUMC research staff honored for excellence in the lab, clinic

Laboratory and administrative personnel at Vanderbilt University Medical Center were honored on March 29 for research excellence during the 20th annual Research Staff Awards Ceremony.

Cell-specific variations in gene regulation may be key to treating pulmonary fibrosis

An international research team co-led by Vanderbilt University Medical Center has revealed how variations in gene regulation in different cell types drive pulmonary fibrosis, a progressive respiratory disorder characterized by scarring and loss of functional lung tissue.

By Bill Snyder

March 28, 2024

VUMC team discovers antibodies that may prevent severe respiratory illness

Using a technique developed at Vanderbilt University Medical Center, researchers identified antibodies that are excellent leads as potential therapies for human parainfluenza virus 3, a leading cause of acute and potentially fatal respiratory illness.

By Bill Snyder

March 28, 2024

Teams to create one-stop resource for human pancreatic data to foster diabetes research

Leading investigators in diabetes, pancreas and islet biology, and computational biology have received $12.5 million in two five-year awards from the National Institutes of Health (NIH) to create the world’s first, integrated knowledge base of human-derived tissue- and cellular-level pancreatic information to support innovative, collaborative and reproducible research.

By Jill Clendening

March 28, 2024

Study identifies molecule as potential target for treating AML

While immune checkpoint inhibitors that target the PD-1 molecule on T-cells have proven to be effective with many cancers, these immunotherapies have not worked for acute myeloid leukemia (AML), but new research has identified a “cousin” molecule as a potential therapeutic target for AML.

By Tom Wilemon

March 27, 2024

Higher genetic risk of obesity means working out harder for same results

Study authors used activity, clinical and genetic data from the National Institutes of Health’s All of Us Research Program to explore the association of genetic risk of higher body mass index and the level of physical activity needed to reduce incident obesity.