Research

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September 30, 2024

VUMC researchers awarded $1.9 million for AI-driven cancer data extraction

The project seeks to reduce the time for clinical chart abstraction by 90% while maintaining human-level accuracy.

By Paul Govern
September 27, 2024

Distant relatedness in biobanks harnessed to identify undiagnosed genetic disease

VUMC researchers have developed a genetic method that clusters distantly related people to find rare variants that were present in a common ancestor.

By Leigh MacMillan
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September 27, 2024

Minor early changes in lungs can signal changes in progressive lung disease

The research focused on the very early stages of FPF, a serious progressive lung disease where for unknown reasons scar tissue builds up in the lungs over time.

By Nancy Humphrey
Co-principal investigators of the genomic-enabled learning health system coordinating center and clinical site are, front row from left, Carolyn Audet, PhD, Alexander Bick, MD, PhD, and Sunil Kripalani, MD, MSc, and, back row from left, Wesley Self, MD, MPH, Josh Peterson, MD, MPH, and Dan Roden, MD. (photo by Susan Urmy)
September 24, 2024

‘Learning’ network will help move genomics into the clinic

A real-world learning health system was established at VUMC a decade ago. Now, the National Human Genome Research Institute is awarding two five-year grants totaling $12 million to support VUMC’s participation in, and coordination of, a genomic-enabled learning health system (gLHS) network.

By Bill Snyder
Image of the U.S., with markers that note cities where the Home Owners’ Loan Corp. conducted a city survey of impacted areas. (Source: Mapping Inequality)
September 24, 2024

Poverty rates linked to asthma in ‘redlined’ areas

Neighborhoods that were discriminated against, called ‘redlined areas,’ are known to have higher levels of air pollution from industry and vehicles, especially diesel-fueled trucks, buses and cars.

By Craig Boerner
Douglas Terry, PhD. (photo by Donn Jones)
September 23, 2024

New study reveals common belief of CTE, link to mental health among former professional NFL players

“Understanding the proportion of former players who think they have CTE — and identifying the common symptoms in those who believe they have CTE — is an important step for helping these individuals receive medical and mental health treatment,” said Douglas Terry, PhD, assistant professor and clinical neuropsychologist in the Department of Neurological Surgery and co-director of the Vanderbilt Sports Concussion Center.

By Holly Fletcher
September 20, 2024

VUMC method tracks down rare, broadly reacting antibodies: study

The discovery, reported in the journal PLOS Pathogens, could help open the door to the development of effective vaccines and antibody therapies with an “exceptional breadth of pathogen coverage.”
By Bill Snyder
September 20, 2024

Fever drives enhanced activity, mitochondrial damage in immune cells

The mechanistic understanding of how cells respond to heat could explain how chronic inflammation contributes to the development of cancer.
By Leigh MacMillan
September 20, 2024

Vanderbilt researchers speaks at World Conference on Lung Cancer

Deppen spoke about biological, population and technology issues related to the discovery and implementation of biomarkers for early cancer detection.
By Tom Wilemon
September 16, 2024

Kidney stone grant to create research resource for adults and children

The project will create the Urinary Stone Disease Hub, known as USDHub, with de-identified patient data from over 230,000 individuals with kidney stone disease across nine health systems in the U.S.
By Craig Boerner
September 13, 2024

VUMC joins national effort to prevent another pandemic

Developed in the wake of the COVID-19 pandemic, ReVAMPP will support a coordinating center and seven research centers, including VUMC, with a focus on nine virus groups that pose the greatest risk to human health.
By Bill Snyder
September 13, 2024

Nominations sought for 2024 Research Staff Awards

The awards honor staff members who provide exemplary support at all levels across the research enterprise. Their contributions to research are unmatched and invaluable to the science conducted at Vanderbilt.
By Bill Snyder
September 11, 2024

Kelly Dooley’s TB research receives MERIT Award from the NIH  

Researchers must continually chase funding for their work. Kelly Dooley's prestigious award from the NIH is intended to help provide respite from that chase.
By Paul Govern