Research

November 21, 2022

Suicide notes

Natural language processing of notes in electronic health records can identify suicidal behavior and could be used to directly improve real-time risk prediction algorithms.

By Paul Govern
November 17, 2022

Surgery for hereditary breast cancer

Similar rates of bilateral mastectomy in women with inherited mutations in high- and moderate-penetrance genes raises concerns about possible overtreatment of some patients, Vanderbilt researchers report.

By Leigh MacMillan
November 17, 2022

A marker for mortality

A urine biomarker of inflammation was associated with increased mortality and multiple lifestyle factors, suggesting that modifications could help reduce premature mortality.

By Sarah E. Glass
Highly multiplexed, untargeted MALDI imaging mass spectrometry data reveal the localization of various lipids and metabolites to specific functional regions of the nephron, the kidney's filtering unit (right).
November 17, 2022

Grants spur efforts to create molecular ‘atlases’ of organs

Vanderbilt researchers have received three grants totaling $13.6 million from the National Institutes of Health to develop molecular “atlases” of the brain, kidney, eye and other tissues.

By Bill Snyder
November 17, 2022

Study supports removing race from estimate of kidney function

An in-depth analysis by Vanderbilt investigators of published research studies supports removing race from the calculation of estimated glomerular filtration rate (eGFR) — an assessment of kidney function.

By Leigh MacMillan
November 17, 2022

Several from VUMC among most highly cited researchers

Nine current faculty members of the Vanderbilt University School of Medicine have made this year’s list of scientists whose papers have been cited most frequently by other researchers.

By Bill Snyder
November 16, 2022

Cardiac antigen identified as mechanism for heart complication with immunotherapy-related myocarditis

Researchers from from Vanderbilt-Ingram Cancer Center have identified the mechanism for the deadly heart inflammation myocarditis.
By Tom Wilemon
November 11, 2022

Study finds inherited link to appendix cancer

A Vanderbilt study is the first to show inherited risk factors for appendiceal cancer.
By Tom Wilemon
November 10, 2022

Hawiger still blazing a trail in inflammation research

Vanderbilt research describes a new investigational peptide drug that can penetrate immune and nonimmune cells, and block inflammatory signaling in a preclinical model of atopic dermatitis — eczema.
By Bill Snyder
November 10, 2022

Clinical trial at VUMC tests novel treatment for asthma

VUMC has begun enrolling patients with asthma in a clinical trial of a novel treatment: a medication approved to treat diabetes and obesity.
By Leigh MacMillan
November 10, 2022

Study defines role of steroids in congenital heart disease surgery

Steroids are commonly given to infants during open-heart surgery to reduce inflammation, but whether the drugs significantly improve patient outcomes has not been settled — until now.
By Bill Snyder
November 8, 2022

Alzheimer’s risk factor and cognition

Vanderbilt researchers found that a protein with roles in innate immunity worsens memory at baseline in carriers of APOE-e4, the strongest genetic risk factor for Alzheimer’s disease, further implicating neuroinflammation in cognitive decline.
By Leigh MacMillan
November 7, 2022

Gene mutations impair gut barrier

Mutations in a cell membrane transporter protein impair the integrity of the gut lining, contributing to chronic gastrointestinal distress for people with the mutations, Vanderbilt researchers report.
By Kelsey Pinckard
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