Research

The system is designed to bypass blocked arteries in the leg and restore blood flow into the foot through the veins.
March 30, 2023

New procedure helps patients avoid leg amputation

More than 75% of patients facing amputation from the most severe form of peripheral artery disease were able to keep their limb after an innovative treatment as part of a multicenter study published in the New England Journal of Medicine.

By Craig Boerner
The study team includes, from left, Maribeth Nicholson, MD, MPH, Ben Spiller, PhD, Buddy Creech, MD, MPH, Borden Lacy, PhD, Eric Skaar, PhD, MPH, Isaac Thomsen, MD, MSCI, Ivelin Georgiev, PhD, and Danyvid Olivares-Villagomez, PhD.
March 30, 2023

NIH grant launches C. diff vaccine research initiative

Vanderbilt has received an NIH grant to launch the Vanderbilt Antibody and Antigen Discovery for Clostridioides difficile Vaccines, or VANDy-CdV.

By Anthony Czelusniak
March 30, 2023

VUMC researcher selected for Global Scholars Program

Vanderbilt researcher P. Brent Ferrell, MD, is leading one of five projects selected by the 2022 Novartis Institutes for BioMedical Research Global Scholars Program.

By Leigh MacMillan
March 30, 2023

Discussing cryo-EM

Yifan Chang, PhD, recently spoke about his team’s research using single particle cryo-EM (cryogenic electron microscopy) to study INO80, an ATP-dependent chromatin remodeling complex.

By VUMC News and Communications
March 28, 2023

Inflammation implicated in exfoliation syndrome

Computational genetics tools have implicated inflammatory pathways in exfoliation syndrome, the most common cause of secondary glaucoma, which can result in blindness.

By Leigh MacMillan
March 27, 2023

Improving lung nodule diagnosis

Adding blood and imaging biomarkers to a clinical prediction model could improve diagnostic accuracy for the 1.6 million lung nodules detected each year, many through expanded lung cancer screening programs.

By Leigh MacMillan
March 23, 2023

Reminders for clinicians improve prescribing for high cholesterol

A Vanderbilt study found that automated targeted reminders for clinicians helped increase prescribing of high intensity statins for patients with various atherosclerotic cardiovascular disease diagnoses, including coronary or peripheral artery disease and ischemic stroke.
By Paul Govern
March 23, 2023

Goldenring’s gastrointestinal research contributions lauded

Vanderbilt's James Goldenring, MD, PhD, has been honored by the American Gastroenterological Association for making significant contributions to understanding gastrointestinal disease.
By Bill Snyder
March 23, 2023

Mathers Foundation award supports study of bacterial physiology

Vanderbilt's Wenhan Zhu, PhD, has received a three-year award from the G. Harold and Leila Y. Mathers Foundation to support his research that aims to answer a fundamental question about bacterial physiology and engineer probiotics to improve gut inflammatory diseases.
By Leigh MacMillan
March 23, 2023

Decoding cell division machinery

Phosphate modification regulates the cell localization of Cdc15, one of the main controllers of cell division, to fine tune the assembly of cell division machinery.
By Caroline Cencer 
March 23, 2023

E. coli uses serine to abide acidity

Vanderbilt researchers have discovered another acid resistance mechanism for UTI-causing E. coli, laying the foundation for targeted antibacterial therapies.
By Cherie Saffold
March 22, 2023

Survey finds patients value immediate access to test results

A survey sent to more than 43,000 patients living in several states around the country finds that 96% of patients who use patient web portals prefer immediate online access to their clinical test results.
By Paul Govern
March 16, 2023

Scientists resurrect a ‘dead’ antibody to study protein

Vanderbilt was part of a multi-center team that resurrected a “dead antibody” to reveal the mysteries of cytochrome c, a versatile protein that is an essential part of the cell’s energy-generating capacity, and of life itself.
By Bill Snyder
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