Research Archive — Page 34 of 131

Jordan Wright, MD, PhD, left, and Adel Eskaros, MBBS, PhD, are lead authors of the report on pancreatic exocrine-endocrine “crosstalk.” (photo by Susan Urmy)
November 1, 2023

Pancreas “crosstalk” may influence course of Type 1 and Type 2 diabetes

In the largest study of its kind, researchers at Vanderbilt have identified unexpected alterations in the exocrine tissues of the pancreas that occur in the two major forms of diabetes, and with aging and obesity.

October 31, 2023

Polygenic ‘scores’ may improve cancer screening

Accounting for genetic variability in biomarkers not associated with cancer risk could avoid unnecessary diagnostic procedures, Vanderbilt researchers found.

Randika “Randy” Perera, PhD, left, Wenhan Zhu, PhD, Walter Chazin, PhD, Luisella Spiga, PhD, Ryan Fansler and colleagues discovered that beneficial bacteria in the gut impact the competition that occurs between host cells and pathogens for the essential nutrient iron. (photo by Erin O. Smith)
October 27, 2023

Study discovers role for gut bacteria in host-pathogen competition for nutrients

Vanderbilt research shows that commensal gut microbes impact the host-pathogen competition for iron and has implications for therapeutic strategies aimed at preventing pathogens from acquiring essential nutrients.

October 25, 2023

Immune system’s role in metabolic disease detailed in tissue atlas

Researchers at Vanderbilt University Medical Center have published the largest known single-site adipose tissue atlas — a comprehensive, detailed map of the cells, structures and molecules within a specific tissue or organ, designed to support open-ended study.

Alyssa Hasty, PhD, left, Jeffrey Rathmell, PhD, and Kamran Idrees, MD, MSCI, are part of a multidisciplinary team that received a 2023 Endeavor Award from The Mark Foundation for Cancer Research to study the connection between obesity and cancer. Team members not pictured include Kathryn Wellen, PhD, Liza Makowski, PhD, and Kathryn Beckermann, MD, PhD.
October 24, 2023

Vanderbilt-led team receives 2023 Endeavor Award from The Mark Foundation for Cancer Research

A multidisciplinary team of investigators has received a 2023 Endeavor Award from The Mark Foundation for Cancer Research to support four closely linked projects exploring the fundamental mechanisms that drive the obesity-cancer connection,

October 17, 2023

AI predicts blood clot risk in hospitalized children: VUMC study

An artificial intelligence tool developed at Vanderbilt accurately identified pediatric patients at high risk for blood clots in a clinical trial, with no difference in outcomes compared to a control group.