Research

May 24, 2022

Diabetes, cardiovascular drug targets

Targeting receptors of the inflammatory lipid signaling molecule PGE2 may offer a new way to tackle both Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered.

By Leigh MacMillan
May 23, 2022

Pushing (anti-overdose) drugs

An automated alert to encourage clinicians to coprescribe naloxone for patients at risk of opioid overdose increased naloxone prescriptions per opioid prescription 16-fold.

By Paul Govern
May 19, 2022

Genetics and blood pressure

Including polygenic risk scores for blood pressure may improve predictive models to identify people at risk for treatment-resistant hypertension.

By Leigh MacMillan
May 19, 2022

A clue to an adverse drug event in children

Considering metabolic (CYP2D6) enzyme activity score and patient age may aid in determining an individual’s risk for an adverse event with administration of the anti-arrhythmic drug propafenone.

By Joshua Baker
Stomach
May 19, 2022

Molecular ‘switch’ may illuminate stomach disorders

An international team that included researchers from Vanderbilt University Medical Center has discovered a molecular switch that induces rapid proliferation of zymogen granule-secreting chief cells in the stomach to regenerate damaged tissue.

By Bill Snyder
Andy Weiss, PhD, Caitlin Murdoch, PhD, and colleagues have characterized the first zinc metallochaperone: a protein that puts zinc into other “client” proteins.
May 17, 2022

Study identifies first cellular “chaperone” for zinc, sheds light on worldwide public health problem of zinc deficiency

A team led by Vanderbilt researchers has described and characterized the first zinc metallochaperone: a protein that puts zinc into other “client” proteins.

By Leigh MacMillan
May 12, 2022

Study sheds light on the dark side of obesity

Vanderbilt research that promotes the anti-inflammatory pathway in macrophages could also reduce some of the bad side effects of obesity.
By Bill Snyder
May 12, 2022

VUMC-led study finds Moderna COVID vaccine safe and effective for children

By Bill Snyder
May 10, 2022

Report lays out solution for pandemic patient privacy

Health information privacy experts at Vanderbilt University Medical Center, the University of Texas at Dallas and IBM have collaborated on a public case reporting framework keyed to the dynamics of pandemics.
By Paul Govern
May 10, 2022

New study illustrates how much it would cost for cancer drugs covered under Medicare Part D

A new study by Vanderbilt researchers highlights how some older Americans diagnosed with cancer can face unlimited out-of-pocket spending for prescription drugs under the current structure of the Medicare Part D benefit.
By Jake Lowary
May 10, 2022

Nominations sought for the 2022 Vanderbilt Prize Student Scholar

Nominations for the 2022 Vanderbilt Prize Student Scholar are invited through May 27.
By VUMC News and Communications
May 10, 2022

Resistance to COVID-19 drug detected in lab study

Vanderbilt research shows that the virus that causes COVID-19 can develop partial resistance to the antiviral drug remdesivir during infection of cultured cells in the laboratory by more than one mechanism.  
By Bill Snyder
May 10, 2022

Autism and sleep problems

Vanderbilt researchers developed a framework for using de-identified medical records to characterize sleep in people on the autism spectrum — a framework that should also be useful for studying other neurodevelopmental disorders.
By Emily Stembridge
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