Research

January 27, 2020

A new contributor to atherosclerosis

Sean Davies and colleagues are exploring lipid aldehydes produced during oxidative stress and their contribution to HDL dysfunction and atherosclerosis.

By Leigh MacMillan
January 23, 2020

Insights on diabetic retinopathy

A drug that targets multiple pathogenic steps in diabetic retinopathy may be an ideal therapeutic strategy for the disease, Vanderbilt researchers report.

By Leigh MacMillan
January 23, 2020

HDL-cholesterol and breast cancer risk

Genetic analyses suggest that high circulating HDL-cholesterol levels may increase breast cancer risk — a surprising finding since increased HDL-cholesterol is thought to be healthy.

By Leigh MacMillan
January 23, 2020

Antibody isolated at VUMC found to halt dengue virus

Using part of an antibody isolated at Vanderbilt that “broadly neutralizes” the human dengue virus, biologists at the University of California San Diego and colleagues have disarmed the mosquito that transmits the disabling and potentially deadly tropical infection.

By Bill Snyder
January 15, 2020

VUMC study to use artificial intelligence to explore suicide risk

Investigators will use computational methods to shed light on suicidal ideation and its relationship to attempted suicide, predict suicidal ideation and suicide attempt using routine electronic health records (EHRs) and explore the genetic underpinnings of both.

By Paul Govern
January 13, 2020

Vanderbilt-led team discovers new genetic disease and defines underlying mechanism

An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms.

By Leigh MacMillan
January 13, 2020

Zinc uptake by a deadly pathogen

The increasingly antibiotic-resistant bacterium Acinetobacter baumannii requires zinc to cause infection, and Vanderbilt researchers have identified the zinc uptake system it uses.
By Leigh MacMillan
January 10, 2020

Bone matrix changes during aging

Changes to the bone matrix that occur during aging may point to novel targets for treating osteoporosis.
By Leigh MacMillan
January 10, 2020

Structural views of a C. diff toxin

D. Borden Lacy and colleagues used cryo-electron microscopy to define the structure of a C. diff toxin, providing a framework for the design of novel therapeutics.
By Leigh MacMillan
January 9, 2020

Impact of weight gain from early to middle adulthood explored

An analysis of weight gain occurring from early to middle adulthood indicates that the added weight is associated with multiple health outcomes in later life.
By Tom Wilemon
December 31, 2019

Kavalali receives Humboldt Research Award

Ege T. Kavalali, PhD, professor and acting chair of the Department of Pharmacology in the Vanderbilt University School of Medicine, has been elected a recipient of a prestigious Humboldt Research Award by the Alexander von Humboldt Foundation of Germany.
By Bill Snyder
December 20, 2019

Tennessee Receives Grant from Federal Government to Address Opioid Crisis

The Division of TennCare will partner with VUMC as part of the MOM program focusing on 26 rural and urban counties to improve the outcomes for women with opioid use disorder and their infants.
By Holly Fletcher
December 20, 2019

Hepatitis C–positive donors a viable option to expand heart donor pool

Hepatitis C-positive heart donors offer a strategy to safely expand the donor pool and allow more patients to undergo transplant.
By Matt Batcheldor
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