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Department of Cell and Developmental Biology Archives

Gut response to fluid flow

Oct. 26, 2017—Vanderbilt researchers have discovered that microvilli – finger-like projections from cells in the intestine – respond to the shear stress of fluid flow to drive a cellular pathway that regulates nutrient balance.

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Researchers find novel mechanism of resistance to anti-cancer drugs

Oct. 17, 2017—Vanderbilt investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings, reported this week in Nature Medicine, suggest a strategy for overcoming this resistance.

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Goal of new tissue-chip research is to assess efficacy of novel epilepsy drugs

Sep. 20, 2017—An interdisciplinary team of Vanderbilt University researchers has received a two-year, $2-million federal grant to develop an “organ-on-chip” model for two genetic forms of epilepsy.

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Epigenetics expert Allis set for Sept. 7 Discovery Lecture

Aug. 31, 2017—Internationally known epigeneticist C. David Allis, Ph.D., will deliver the first Flexner Discovery Lecture of the academic year at 4 p.m. Thursday, Sept. 7, in room 208 Light Hall.

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Discovery sheds light on protein key to nerve cells’ myelin sheath

Aug. 17, 2017—Genetic mutations in PMP22 (peripheral myelin protein 22) cause a variety of peripheral neuropathies, underscoring the importance of the protein to a healthy peripheral nervous system. But the precise function of PMP22, a major component of the myelin sheath that surrounds and insulates peripheral nerve cell axons, has been unclear.

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NOTCH1 role in heart development

Jul. 3, 2017—The identification of a genetic culprit for hypoplastic left heart syndrome could lead to new treatments for the condition.

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A molecular clue to longevity

Mar. 31, 2017—In budding yeast, accumulation of a certain type of RNA in the nucleus increased life span, offering a new clue to longevity.

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Molecular motors expert Spudich set for next Discovery Lecture

Mar. 30, 2017—James Spudich, Ph.D., renowned for his studies of proteins that function as molecular motors, will deliver the next Flexner Discovery Lecture on Thursday, April 6.

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Memorial service for Professor Vivien Casagrande set for April 12

Mar. 24, 2017—A memorial service for Professor Vivien Casagrande is planned for April 12 in Benton Chapel.

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Recent Stories from VUMC News and Communications Publications

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

Vanderbilt University Adult Hospital with helipad

Vanderbilt University Adult Hospital with helipad

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