Suman Das

ELVIS team leaders include, from left, Jane Freedman, MD, project leader Suman Das, PhD, Simon Mallal, MBBS, Ravi Shah, MD, John McLean, PhD. (photo by Erin O. Smith)

$51 million NIH grant brings ELVIS to VUMC

Vanderbilt University Medical Center scientists are launching a research platform called ELVIS that is devoted to molecular underpinnings of early-childhood determinants of health.

COVID alters respiratory microbiota

COVID-19 infection alters the microbes of the upper respiratory tract for at least several weeks, and such disturbances could impact disease severity and be targets for therapeutic interventions.

Study finds RSV may evade vaccines via rapid mutation

A Vanderbilt study concluded that RSV’s ability to mutate rapidly to escape detection by the body’s immune system makes it more challenging to design and develop vaccines that can stop it from spreading.

COVID-19 battle begins in the nose

A high upper airway concentration of the virus that causes COVID-19 was associated with changes in gene expression that could impact disease progression, Vanderbilt researchers discovered.

Microbiome reflects COVID-19 severity

Characterization of the upper respiratory tract microbiome could help predict outcomes for COVID-19 infection, Vanderbilt researchers have discovered.

Who’s who in the respiratory landscape

A metatranscriptomics method developed by Vanderbilt researchers simultaneously characterizes viruses, microbiome and host response in nasal swabs, opening opportunities to explore molecular interactions directly in clinical samples.