An estimated 200,000 people in the United States have lupus. About 80% of them experience “brain fog,” cognitive problems that impair learning, memory and attention. The EG501 study was the inaugural project of Vanderbilt Health’s Drug Repurposing program.

These findings highlight the critical need for tumor genomic testing for all patients to identify those with high-risk tumors, which occur more frequently in Black women, and which require more aggressive treatment to prevent recurrence.

The potential for a retinal screening test was bolstered by a recent discovery that clearance of amyloid-beta oligomers by immune cells in retinal blood vessels was disrupted in donor eyes from individuals with Alzheimer’s disease, compared to age-matched, healthy control eyes.

These findings shed light on disruptions in normal blood cell development (hematopoiesis) that may be shared by sickle cell disease and clonal hematopoiesis.

“These antibodies hold significant promise to be used in people who are at risk of measles, but who cannot respond to the measles vaccine due to their weakened immune systems," said James Crowe Jr., MD, whose research team isolated the human monoclonal antibodies.

The 2025 fellows have been invited to the annual AAAS Fellows Forum May 29 in Washington, D.C.