Leigh MacMillan

October 21, 2019

Completing DNA synthesis

James Dewar and colleagues have identified a role for the enzyme topoisomerase II in reducing replication errors during the final stage of DNA synthesis.

By Leigh MacMillan
October 17, 2019

Microscopic spines connect worm neurons

Worm neurons have microscopic “spines” — where nerve-to-nerve communication happens — that share features with mammalian neurons, supporting the use of worms to study spine genetics and biology.

By Leigh MacMillan
October 10, 2019

NIH bioethics expert Grady set for next Discovery Lecture

Nurse-bioethicist Christine Grady, MSN, PhD, chief of the Department of Bioethics at the National Institutes of Health (NIH) Clinical Center, will deliver the next Flexner Discovery Lecture on Thursday, Oct. 17.

By Leigh MacMillan
3d rendering white blood cells with red blood cells
October 8, 2019

A new regulator of B cell development

New findings establish a role for the pro-inflammatory molecule IL-33 in the early development of antibody-producing B cells.

By Leigh MacMillan
October 3, 2019

A catalog of DNA replication proteins

Vanderbilt scientists have identified 593 proteins that are enriched at sites of DNA duplication and chromatin packaging of newly synthesized DNA.

By Leigh MacMillan
October 1, 2019

Pua lands NIH Director’s New Innovator Award

Heather Pua, MD, PhD, one of 60 investigators to receive the 2019 NIH Director’s New Innovator Award, will explore a novel type of cell signaling by RNAs in allergic airway inflammation.

By Leigh MacMillan
September 23, 2019

Tailoring treatment for heart defect

By defining the clinical and genetic factors that predict treatment response, Vanderbilt investigators aim to personalize therapy for a common heart complication in preterm infants.
By Leigh MacMillan
September 19, 2019

Gamazon receives NIH Genomic Innovator Award

VUMC's Eric Gamazon is one of only six investigators to receive an inaugural Genomic Innovator Award from the National Human Genome Research Institute, part of the NIH.
By Leigh MacMillan
September 19, 2019

Potential prostate cancer biomarkers

An analysis of more than 140,000 people of European ancestry has identified blood protein biomarkers associated with prostate cancer risk.
By Leigh MacMillan
September 12, 2019

Metabolism expert Lazar set for next Discovery Lecture

Endocrinologist Mitchell Lazar, MD, PhD, known for his work on the genetic regulation of metabolism, will deliver the next Flexner Discovery Lecture on Thursday, Sept. 19.
By Leigh MacMillan
September 9, 2019

Astrocytes and epilepsy

A protein with important functions in astrocytes — star-shaped brain support cells — may alter neuronal excitability and contribute to seizure activity, Vanderbilt researchers report.
By Leigh MacMillan
September 5, 2019

How salt increases blood pressure

Vanderbilt researchers have discovered that a protein called SGK1 in immune cells is activated by sodium, leading to the development of salt-sensitive hypertension.
By Leigh MacMillan
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