Leigh MacMillan

concept illustration of knee with pain radiating from it
November 1, 2017

Bioactive lipids and rheumatoid arthritis

An enzyme that produces bioactive fatty acids has elevated activity in patients with rheumatoid arthritis, supporting further studies to understand its biologic roles in the disease.

By Leigh MacMillan
October 30, 2017

Disparities in influenza outcomes

Neighborhood determinants – represented by census tract data – contribute to the risk of influenza hospitalization and could be used to guide interventions such as vaccinations to high-risk areas.

By Leigh MacMillan
October 18, 2017

Calcium intake and colorectal cancer

Calcium intake appears to protect against colorectal cancer in individuals with certain gene variants, Vanderbilt researchers have discovered.

By Leigh MacMillan
October 17, 2017

Researchers find novel mechanism of resistance to anti-cancer drugs

Vanderbilt investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings, reported this week in Nature Medicine, suggest a strategy for overcoming this resistance.

By Leigh MacMillan
October 13, 2017

New tools to combat kidney fibrosis

Vanderbilt investigators have developed a new mouse model of kidney fibrosis, which provides a platform for identifying new targets and treatment strategies.

By Leigh MacMillan
October 12, 2017

Researcher targets peanut allergies with Cohen Fund support

Scott Smith, M.D., Ph.D., assistant professor of Medicine, has received a 2017 research award from the Stanley Cohen Innovation Fund to test a new therapeutic strategy for peanut allergies. Smith’s research could fundamentally change allergy treatment.

By Leigh MacMillan
October 4, 2017

Boosting sarcoma cell death

A compound identified at Vanderbilt represents a new lead for treating rare, aggressive childhood cancers called Ewing sarcomas.
By Leigh MacMillan
September 29, 2017

Novel insights to antibiotic targets

New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines.
By Leigh MacMillan
September 28, 2017

Cellular calcium handling in diabetes

Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health.
By Leigh MacMillan
September 28, 2017

VU scientists discuss cancer treatments, cellular dynamics

A trio of Vanderbilt University scientists described their cutting-edge investigations of cellular dynamics and cancer treatment during last week’s Flexner Discovery Lecture.
By Leigh MacMillan
September 21, 2017

Excess dietary manganese increases risk of staph infection in heart

Too much dietary manganese — an essential trace mineral found in leafy green vegetables, fruits and nuts — promotes infection of the heart by the bacterium Staphylococcus aureus (“staph”).
By Leigh MacMillan
September 20, 2017

NSAIDs, genetics and miscarriage

A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage.
By Leigh MacMillan
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