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Author: Leigh MacMillan

Stomach bug alters tumor suppressor

Oct. 23, 2012—The stomach bug Helicobacter pylori increases forms of a protein that promote tumor development, perhaps explaining how it elevates risk for gastric cancer.

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Gene regulation found to play role in pulmonary hypertension

Oct. 18, 2012—New findings from Vanderbilt researchers may explain why only some individuals who have inherited mutations that increase risk for pulmonary hypertension actually develop the disease.

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Setting traps to probe gene function

Oct. 18, 2012—A new method for creating genetic mutations that can be activated at certain times or in specific tissues will enable studies to probe gene function.

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Amish aid search for Alzheimer’s genes

Oct. 11, 2012—An analysis of Amish populations revealed novel risk genes for late-onset Alzheimer disease.

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Host proteins can control HIV infection

Oct. 5, 2012—The protein APOBEC3G contributes to spontaneous control of HIV-1 in vivo and may provide therapeutic benefits.

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Proteins help flip tumor’s invasive switch

Oct. 4, 2012—Vanderbilt investigators have identified how two key components of cancer's invasive "switch" — the series of signaling events that turn on a tumor cell’s invasive behavior — work together.

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Cell entry ports for cold virus

Sep. 25, 2012—The respiratory virus HMPV uses its fusion (F) protein – which interacts with cellular receptors called integrins – to bind to and enter target cells.

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How ‘Jedi’ disposes of dead neurons

Sep. 19, 2012—The protein Syk is essential for clearing away neuron “corpses” in the developing peripheral nervous system.

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Cells with LIP eat their neighbors

Sep. 13, 2012—A transcription factor called LIP is capable of causing one cell to consume another.

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New doctoral students welcomed

Sep. 6, 2012—Vanderbilt University Medical Center welcomed 109 new doctoral students into the scientific community last week in the third annual “Simple Beginnings” ceremony.

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Neuronal subtypes in genetic disorder

Sep. 6, 2012—Inhibitory neurons that connect and regulate signaling in the brain (interneurons) may contribute to epilepsy and autism in patients with tuberous sclerosis complex.

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Targeting new pathways to ease pain

Aug. 30, 2012—The spinal cord’s neuropeptide Y signaling pathway may be a good target for new pain therapeutics.

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Recent Stories from VUMC News and Communications Publications

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer.  Don’t hesitate. Do it.

Momentum

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer. Don’t hesitate. Do it.

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

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