Leigh MacMillan Archive — Page 48 of 83

August 3, 2017

HDAC3 role in B-cell development

The histone deacetylase HDAC3 is required for the maturation of B cells, white blood cells that produce antibodies.

July 21, 2017

Probing the genetics of autoimmunity

Vanderbilt researchers have found that non-coding regions of the genome appear to contribute to the risk of autoimmune diseases and may represent attractive therapeutic targets.

July 20, 2017

Drivers of breast cancer metastasis

Signaling through a complex of proteins called mTORC2 plays a role in breast cancer migration, invasion and metastasis, Vanderbilt researchers reported.

bacteria microbiome
July 5, 2017

Bile acids, microbiota and colon cancer

Bile acids produced by a western diet alter the composition of the gut microbiota and promote intestinal carcinogenesis.

June 29, 2017

Team investigates antiviral that inhibits SARS, MERS

A new antiviral drug candidate inhibits a broad range of coronaviruses, including the SARS and MERS coronaviruses, a multi-institutional team of investigators reports this week in Science Translational Medicine.

June 14, 2017

PET imaging to predict tumor response

A PET probe that detects the amino acid glutamine predicts whether tumors respond to certain targeted therapies in preclinical animal models.