The signaling molecule IL-15 promotes septic shock, a life-threatening condition involving organ injury caused by infection.

Vanderbilt researchers have identified a unique example of communication between bacterial signaling systems, which may have relevance for antibiotic resistance.

High dose flu vaccine boosts the immune response in older adults by increasing activation of certain immune cells.

Although cancers arising from different areas of the large intestine are heterogeneous, they appear to use similar important tumorigenic pathways.

Metastatic pancreatic cancer — cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths — changes its metabolism and is “reprogrammed” for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics.

Vanderbilt investigators recommend that the presence of tumor deposits in the abdomen be included when staging midgut neuroendocrine tumors.