Leigh MacMillan

In search of new asthma therapies

A peptide molecule relaxes airway smooth muscle and may be a potential therapeutic for asthma that has become resistant to standard therapies.

New culprit in nerve degeneration

Vanderbilt researchers have discovered that regulation of cell volume plays a role in nerve degeneration and peripheral neuropathies.

Pregnant woman holding pill pack

Fetal impact of antidepressants

Antidepressant use during pregnancy is common. Fetal exposure to the class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) is associated with the life-threatening condition PPHN (persistent pulmonary hypertension of the newborn), but a causal link has not been established.

Refining neural circuitry

During development, neural circuits are remodeled – some synapses are eliminated and others are strengthened – to produce a mature, functional nervous system.

lungs

Marrow cells’ role in pulmonary hypertension explored

Cells from the bone marrow participate in the development of pulmonary arterial hypertension (PAH), and they can also protect against it, according to new findings from a team of Vanderbilt University Medical Center investigators.

Work together to control diabetes

Parenting behaviors may be an important target for improving outcomes in adolescents with diabetes.

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