Leigh MacMillan

January 2, 2015

Genome-editing pioneer next up in Discovery Lecture series

Jennifer Doudna, Ph.D., recipient of a 2015 Breakthrough Prize in Life Sciences, will deliver the next Flexner Discovery Lecture on Thursday, Jan. 8.

By Leigh MacMillan
Heart illustration thumbnail
December 18, 2014

Atrial disease and hypertension links

New findings suggest that misfolded proteins accumulate in the heart atria, particularly in patients with hypertension, and may contribute to atrial heart disease.

By Leigh MacMillan
December 17, 2014

Target for atherosclerosis therapies

A newly identified “atheroprotective” gene is a tool for exploring plaque pathophysiology and may be a good target for therapies to slow atherosclerosis progression.

By Leigh MacMillan
December 16, 2014

Retinal neuron survival in glaucoma

Understanding how the protein TRPV1 helps neurons survive after glaucoma-related stressors could lead to new therapeutic strategies for glaucoma and other neurodegenerative conditions.

By Leigh MacMillan
December 11, 2014

Bacterial secretion machinery: 3-D view

New structural findings reveal how “gatekeeper” proteins participate in the secretion systems bacteria use to infect host cells.

By Leigh MacMillan
December 4, 2014

Columbia’s Bakken to deliver Flexner Discovery Lecture

Suzanne Bakken, Ph.D., RN, the Alumni Professor of Nursing and professor of Biomedical Informatics at Columbia University, will deliver the next Flexner Discovery Lecture on Thursday, Dec. 11.

By Leigh MacMillan
December 4, 2014

Physician-scientist is dream job for Vanderbilt’s Cassat

Jim Cassat, M.D., Ph.D., a pediatric infectious disease specialist who joined the Vanderbilt faculty this summer, loves taking care of children with bone infections and doing research to understand the host-pathogen interactions during these invasive infections.
By Leigh MacMillan
November 26, 2014

New tools to probe manganese biology

Vanderbilt researchers have developed tools to probe the role of the essential metal manganese in neurons, and which offer a started point for developing therapeutic agents for manganese-related neurological disorders.
By Leigh MacMillan
November 21, 2014

Host sequesters zinc to control stomach bug

Understanding how zinc and the host’s immune response control H. pylori’s cancer-causing potential could suggest new therapeutic strategies to reduce infection and cancer risk.
By Leigh MacMillan
October 30, 2014

VU study reveals factor’s new role in cell division, migration

Vanderbilt University investigators have discovered a new molecular mechanism that regulates microtubule dynamics. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery.
By Leigh MacMillan
October 24, 2014

Immune cells’ role in hypertension

Vanderbilt researchers have discovered that certain immune cells contribute to the development of hypertension, suggesting novel targets for treating the disease.
By Leigh MacMillan
October 16, 2014

Staph ‘gangs’ share nutrients during infection: study

Antibiotic-resistant bacteria can share resources to cause chronic infections, Vanderbilt investigators have discovered. The findings shed light on a long-standing question in infectious diseases and may inform new treatment strategies.
By Leigh MacMillan
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