Leigh MacMillan

obesity or overweight belly
July 17, 2014

Study examines therapeutic bacteria’s ability to prevent obesity

Engineered bacteria that produce a therapeutic compound in the gut prevent obesity in mice, Vanderbilt University investigators have discovered.

By Leigh MacMillan
July 17, 2014

Regulating immune regulators

Understanding how to control the generation of regulatory T cells could have important implications for treating autoimmunity and cancer.

By Leigh MacMillan
July 10, 2014

Molecular ‘chat’ holds kidney fibrosis clues

A novel molecular “conversation” regulates kidney fibrosis – the final result of end-stage chronic kidney disease – suggesting new treatment options for this currently irreversible process.

By Leigh MacMillan
July 9, 2014

Study finds ‘hot’ frogs fight off fungal pathogen

Simple heat treatments may give the frog immune system a boost and help it fight off a deadly fungal pathogen, according to a new study published July 10 in the journal Nature.

By Leigh MacMillan
July 7, 2014

Bringing Cancer to Light: Radiology’s invisible energies play lead role in cancer care

By Leigh MacMillan
June 16, 2014

Factor impacts bone toughness

The factor ATF4 has a role in the toughness of bone and its resistance to fracture, suggesting new therapeutic targets.

By Leigh MacMillan
June 13, 2014

How ABC transporters move molecules

New views of how transporters move molecules across cell membranes are key to understanding how these proteins impact tumor cell drug resistance and inherited diseases such as cystic fibrosis.
By Leigh MacMillan
May 29, 2014

Pioneers of Discovery: Investigator taps into artistic side to reveal cells’ secrets

Dylan Burnette, Ph.D., points to one of the many striking photographs on his office walls. It’s a picture of a cell — a microscopic image showing yellow squiggles, bright purple lines and a turquoise oval on a black background, and it looks like abstract art.
By Leigh MacMillan
May 29, 2014

Exploring Wilms tumor race disparity

Unique molecular "fingerprints" could explain the disparity in Wilms tumor incidence and point to novel, race-specific therapeutic targets.
By Leigh MacMillan
May 27, 2014

Respiratory virus vaccine candidate

Virus-like particles containing a protein from human metapneumovirus are a promising vaccine candidate for this respiratory virus.
By Leigh MacMillan
May 23, 2014

Repair protein’s DNA recognition motif

Insights into the workings of DNA damage response proteins such as SMARCAL1 could suggest new ways to improve genome integrity and prevent cancer.
By Leigh MacMillan
May 15, 2014

Biomedical Sciences graduates driven by promise of discovery

Most people probably don’t think much about the chemical compound that flavors curries and gives the Indian spice turmeric its yellow color. For Odaine Gordon, Ph.D., who celebrated his doctoral degree at last week’s Graduate School commencement, this compound — called curcumin — has special significance.
By Leigh MacMillan
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