Leigh MacMillan

February 28, 2013

Starting up protein synthesis, in yeast

Researchers have found an unusual interaction between a factor that “turns on” protein synthesis and one that produces fatty acids.

By Leigh MacMillan
February 21, 2013

Antibacterial protein’s molecular workings revealed

Vanderbilt investigators report new insights to the workings of calprotectin, an immune system protein that “starves” bacterial pathogens of the metal nutrients they require.

By Leigh MacMillan
February 20, 2013

Factor CITED in pediatric liver cancer

Vanderbilt researchers report that they have found a factor involved in the persistence of embryonic cells implicated in childhood liver cancer.

By Leigh MacMillan
February 14, 2013

Cell connections key in valve disease

A protein that connects cells together participates in the calcification that occurs in heart valve disease.

By Leigh MacMillan
February 7, 2013

Study tracks genes involved in heart rhythm disorders

A team led by Vanderbilt University investigators has discovered two new genes — both coding for the signaling protein calmodulin — associated with severe early-onset disorders of heart rhythm.

By Leigh MacMillan
February 6, 2013

Linking oxygen, iron and red blood cells

The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance.

By Leigh MacMillan
February 4, 2013

Brain tumor TIP reveals new target

The protein TIP-1 appears to be a novel prognostic marker for glioblastoma and may be a good therapeutic target for disrupting tumor-driven blood vessel development.
By Leigh MacMillan
February 1, 2013

Cell source of heart’s blood vessels

An unexpected group of cells generates the coronary arteries and may be useful for regeneration therapies following injury to the heart.
By Leigh MacMillan
January 31, 2013

Nobel laureate explores genomics of immune response

In a wide-ranging lecture that moved from plants to nematode worms to human leukemia, Nobel laureate Andrew Fire, Ph.D., outlined his vision for a genomics-based understanding of how organisms respond to novel information.
By Leigh MacMillan
January 31, 2013

Do-it-yourself repair in the kidney

The kidney can mediate its own repair through proliferation of resident immune system cells.
By Leigh MacMillan
January 23, 2013

New view of DNA processing ‘hub’

Structural studies reveal a new framework for understanding a central player in DNA processing.
By Leigh MacMillan
January 21, 2013

HDL cholesterol impaired in kidney disease

HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk.
By Leigh MacMillan
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