Author: Leigh MacMillan
Studies combine genetic testing, electronic health records to find undiagnosed diseases
Apr. 28, 2022—Combining genetic testing with information from electronic health records revealed undiagnosed heart rhythm disorders and new conditions associated with inherited cancer gene mutations.
Calculating risk for uterine fibroids
Apr. 26, 2022—Vanderbilt researchers have constructed a polygenic risk score for uterine fibroids that will be useful for exploring causes of these benign tumors and identifying novel drug targets and therapies.
Molecular testing across tumor types
Apr. 25, 2022—The KRAS inhibitor sotorasib is newly approved for one kind of lung cancer; Vanderbilt researchers ask if it should be considered for another type if the tumor has the gene mutation it targets.
Addiction researcher Nestler set for next Discovery Lecture
Apr. 13, 2022—Eric Nestler, MD, PhD, renowned for his studies of the molecular basis of drug addiction and depression, will deliver the next Discovery Lecture on Thursday, April 21.
Financial impact of prior authorization
Apr. 12, 2022—Prior authorization — health insurer approval of a medical intervention prior to treatment — costs more than $40 million for U.S. academic radiation oncology practices, with questionable value added to patient care.
Peptides promote AFib arrhythmia
Apr. 11, 2022—Peptide oligomers have detrimental metabolic effects and cause pro-arrhythmic electrophysiological changes in heart atria, suggesting they may contribute to atrial fibrillation.
Study advances understanding of bacterial bioterrorism agent
Apr. 7, 2022—Vanderbilt researchers have identified a critical regulatory factor in the bacterium that causes the disease anthrax and has been used as a biological weapon.
Stress in young adult cancer patients and caregivers
Mar. 24, 2022—Adolescent and young adult oncology patients and caregivers experience psychosocial impairment and financial toxicity at the time of cancer diagnosis, findings that will inform interventions to support patient and caregiver well-being.
High blood pressure genes improve heart surgery survival in children
Mar. 24, 2022—Vanderbilt researchers have found that children with a genetic makeup that predicts high blood pressure as adults are more likely to survive congenital heart defect repair surgery.
Discovery Lecture featuring Sánchez Alvarado returns to in-person format
Mar. 17, 2022—Alejandro Sánchez Alvarado, PhD, executive director and chief scientific officer of the Stowers Institute for Medical Research in Kansas City, Missouri, will discuss tissue regeneration at the next Discovery Lecture, in person on Thursday, March 24 in 208 Light Hall.
Probing cancer cell invasion
Mar. 1, 2022—The rigidity of the extracellular matrix that surrounds cells impacts the contractile and invasive properties of head and neck cancer cells.
PET imaging probe for Alzheimer’s disease
Feb. 24, 2022—Vanderbilt researchers report on a new PET imaging probe that will be useful for exploring Alzheimer’s disease pathology.