William Tansey and colleagues identified proteins that interact with the cancer drug target WDR5 and are important for cancer cell growth.
Oxidative stress and toxic products called isolevuglandins in mitochondria play a role in endothelial dysfunction and hypertension — and getting rid of them with a special “scavenger” molecule has therapeutic potential.
Small RNAs — short stretches of genetic material — from microbes may be playing a role in rheumatoid arthritis and other autoimmune diseases.
Vitamin D protection against colon cancer varies according to parathyroid hormone response, particularly among women.
An automated system using keyword searches can help identify candidates for clinical trials on adverse drug reactions.
Geographically targeted efforts to prevent children being placed in out-of-home care might be possible, Vanderbilt researchers report.