Aliquots - Research Briefs

December 9, 2016

Protecting the blood-brain barrier

Vanderbilt investigators have discovered how a promising cancer immunotherapy causes brain swelling, findings that could lead to ways to protect brain function while fighting cancers.

By Sanjay Mishra
Insulin in vials
December 8, 2016

Making human beta cells reproduce

A new method developed at Vanderbilt will speed the search for potential therapeutics for diabetes: compounds that stimulate the replication of insulin-producing beta cells.

By VUMC News and Communications
November 23, 2016

Reducing antidepressants’ side effects

Vanderbilt investigators have discovered how antidepressant medicines that block serotonin uptake can increase bleeding risk.

By VUMC News and Communications
November 21, 2016

Building the basement membrane

Vanderbilt researchers have discovered steps in the regulation of a key enzyme that builds the basement membrane, a structure that undergirds nearly all animal tissues.

By Bill Snyder
November 18, 2016

Targeting the “un-targetable”

A novel drug that targets the protein RSK blocked aggressive breast cancers from metastasizing in an animal model.

By VUMC News and Communications
November 17, 2016

Stem cells promote tolerance

Blood-forming stem cells play a role in immune tolerance and acceptance of organ transplants, Vanderbilt researchers have discovered.

By Leigh MacMillan
November 10, 2016

Protein structure and epilepsy severity

Understanding how mutations affect the structure and function of inhibitory neurotransmitter receptors will shed light on the mechanisms underlying some types of epilepsy.
By VUMC News and Communications
November 8, 2016

Improving wound healing

Vanderbilt researchers have shown that an injectable material improves wound healing and may be useful for large skin wounds such as those in patients with diabetes.
By Leigh MacMillan
November 4, 2016

Probing drug abuse circuitry

Vanderbilt researchers have identified cocaine-induced modifications at specific neuronal connections, which could aid the development of new therapies for substance abuse disorders.
By Leigh MacMillan
November 3, 2016

A DARPP role in gastric cancer

Vanderbilt researchers have discovered a link between Helicobacter pylori infection, inflammation and gastric cancer that could suggest new anti-cancer therapies.
By Sanjay Mishra
October 26, 2016

Single-cell study of tumor samples

A new method for analyzing cells in fixed biopsy tissues from patients by guide personalized treatment strategies for cancer.
By Leigh MacMillan
October 24, 2016

Sleep issues in children with diabetes

Lengthening sleep duration and reducing sleep disturbances in children with type 1 diabetes may improve diabetes outcomes and reduce parental stress.
By Leigh MacMillan
October 21, 2016

DNA damage response protein

Vanderbilt researchers have determined that a previously uncharacterized protein responds to DNA replication stress and has an essential role in maintaining the integrity of the genome.
By Bill Snyder
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