Aliquots - Research Briefs

Insulin in vials
May 14, 2014

CaMKII enhances insulin secretion

The protein CaMKII acts as a calcium sensor in a positive feedback pathway that enhances glucose-stimulated insulin secretion.

Heart illustration thumbnail
May 12, 2014

Normalizing calcium flux to treat atrial fibrillation

A particular anti-arrhythmia drug provides a targeted treatment for certain forms of atrial fibrillation.

May 9, 2014

Bypassing DNA damage

Studies of a human polymerase that replicates DNA have provided a complete kinetic and structural framework for understanding how the enzyme accurately bypasses DNA damage.

May 8, 2014

PET probe detects dying tumor cells

A novel PET imaging probe detects tumor cell death in vivo and could be useful for personalizing cancer medicine.

April 30, 2014

Potential mechanism for myeloma drug’s variable toxicity

A genetic variant is associated with toxicity of the chemotherapy drug melphalan, and could guide individualized dosing for the medication.

April 28, 2014

Target cell entry to halt Chikungunya virus

Understanding how chikungunya virus binds to and enters cells offers a new target for antiviral medications.