Aliquots - Research Briefs

March 19, 2014

Small molecule protects kidney filter

A compound identified at Vanderbilt has therapeutic potential in protecting the kidney filter barrier.

By Bill Snyder
March 17, 2014

Delirium increases long-term disability

Patients who suffer a longer duration of delirium in the intensive care unit are more likely to experience long-term disability after discharge.

By Leigh MacMillan
March 14, 2014

Protein boosts retinal neuron survival

An ion channel protein called TRIPV1 helps retinal neurons survive the elevated eye pressure associated with glaucoma.

By Leigh MacMillan
March 13, 2014

A new way to target cancer-driver Ras

Vanderbilt researchers have discovered small molecules that turn off cancerous Ras signals in a new way.

By Leigh MacMillan
March 5, 2014

Web tool speeds pulmonary hypertension discovery

The pulmonary arterial hypertension knowledgebase (PAHKB), developed by Vanderbilt researchers, provides a useful tool for identifying PAH-related genes and signaling pathways relevant to pathogenesis.

By VUMC News and Communications
March 3, 2014

Dismantling staph’s drug resistance

Targeting the enzyme FosB could make antibiotic-resistant staph bacteria sensitive to the antibiotic fosfomycin.

By Leigh MacMillan
February 28, 2014

Imaging guides Alzheimer gene search

Using imaging data, Vanderbilt researchers discovered an association between a gene pair and brain changes in Alzheimer’s disease.
By Leigh MacMillan
February 27, 2014

Probing the pathogenesis of leukemia

A new mouse model reveals gene clusters important in a treatment-resistant form of leukemia.
By Leigh MacMillan
February 12, 2014

Obesity sends immune cells to the brain

Obesity causes peripheral immune cells to move to the brain, where they may contribute to inflammation and the pathophysiology of obesity.
By Leigh MacMillan
February 10, 2014

Keeping the beat after heart surgery

Variation in the gene for the beta-1 adrenergic receptor increases the risk that a patient will have an abnormal heart rhythm after cardiac surgery.
By Leigh MacMillan
February 7, 2014

New direction for treating lung cancer

Targeting the production of molecules that promote tumor blood vessel development offers a new path for treating lung cancer.
By Leigh MacMillan
February 6, 2014

Antioxidants promising for rare disorder

The antioxidant vitamin E prevented the buildup of toxic products in a model of a rare genetic disorder, suggesting new strategies for therapeutic development.
By Bill Snyder
January 29, 2014

Is healthy obesity possible?

It might be possible to generate a “metabolically healthy” state of obesity by targeting signaling pathways that improve insulin sensitivity.
By Leigh MacMillan