Health and Medicine

April 5, 2016

Immune defenses in asthma

Vanderbilt researchers show that a certain factor negatively impacts the first-line responder cells in the lungs, providing one explanation for why patients with asthma are at greater risk for invasive bacterial disease.

By Leigh MacMillan
DNA sequence visualization
April 4, 2016

VUMC and Celgene Corporation enter into research agreement to accelerate development of next-generation therapeutics

Vanderbilt University Medical Center has entered into a strategic research agreement with Celgene Corporation, a biopharmaceutical company based in Summit, New Jersey.

By Bill Snyder
DNA sequence visualization
April 1, 2016

New role identified for p73 gene

The p73 gene is required for the generation of cilia – hair-like projections on cells – findings that could have implications for the study of lung diseases and sterility.

By VUMC News and Communications
March 31, 2016

Study looks at doctors’ response to genetic testing

A new clinical implementation study from Vanderbilt University Medical Center measures how physicians have responded to the introduction of routine genetic testing to predict patient response to the commonly prescribed antiplatelet drug clopidogrel.

By Paul Govern
March 31, 2016

Cancer prevention and poverty

A new epidemiological study supports smoking cessation and avoidance of sedentary lifestyle as cancer prevention measures.

By Paul Govern
March 23, 2016

Readmission prediction face-off

Using patients’ health records to assess preparedness for hospital discharge is more effective at predicting readmission or death than commonly used questionnaires.

By Paul Govern
March 22, 2016

New treatment for Crohn’s disease

A new biological therapy, ustekinumab, improves markers of disease activity in patients with severe Crohn’s disease.
By Leigh MacMillan
March 21, 2016

Putting schizophrenia to bed

A new compound developed at Vanderbilt treats multiple symptoms of schizophrenia in an animal model, without causing sedation.
By VUMC News and Communications
March 17, 2016

ROCKs and cancer invasion

The rigidity of the microenvironment around cancer cells drives invasive behavior through distinct ROCK signaling pathways, which could guide the development of specific anti-invasive therapies.
By Sanjay Mishra
March 17, 2016

Study suggests cancer’s ‘clock’ can be rewound

Researchers at Vanderbilt University Medical Center have “turned back the clock” in a mouse model of metaplasia — precancerous stomach lesions — raising hopes that gastric cancer, a worldwide scourge that’s rising in the United States, can be prevented.
By Bill Snyder
March 17, 2016

Study explores gene’s role in protecting HIV patients from TB

An international research team led by scientists from Vanderbilt University Medical Center has identified a genetic variant that protects people with HIV from developing active tuberculosis. The variant is near the gene encoding the infection-fighting cytokine IL-12.
By Bill Snyder
March 17, 2016

Study explores carb-loading’s effect on heart

Drinking a high carbohydrate shake can have an acute and detrimental effect on heart function, a study published in the Journal of the American College of Cardiology (JACC) has found.
By Kathy Whitney
March 10, 2016

IOM study calls for better evidence for biomarker tests

Biomarker tests that help determine which patients may benefit from molecularly targeted therapies need better evidence and oversight to improve their effectiveness and availability, according to a study by the Institute of Medicine (IOM) of the National Academies of Sciences, Engineering, and Medicine.
By VUMC News and Communications
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